The Cochrane Hepato-Biliary Group (The CHBG) is one of the fifty-three international research publishing groups within Cochrane (formerly The Cochrane Collaboration).

Cochrane Review Groups are members of one of eight Networks: Abdomen and Endocrine (to which the CHBG belongs); Acute and Emergency Care Cancer; Children and Families; Circulation and Breathing; Mental Health and Neuroscience; Musculoskeletal, Oral, Skin and Sensory; and Public Health and Health Systems.

The CHBG shares the same aim as the other Cochrane groups, which is to provide reliable information to practitioners, policy and decision makers, and consumers. The CHBG strives to achieve this through production, maintenance, and dissemination of hepato-biliary systematic reviews. 

The following types of Cochrane systematic reviews exist:

  • Intervention reviews assess the benefits and harms of interventions used in healthcare and health policy. 
  • Diagnostic test accuracy reviews assess how well a diagnostic test performs in diagnosing and detecting a particular disease.
  • Prognosis reviews address the probable course or future outcome(s) of people with a health problem.
  • Methodology reviews address issues relevant to how systematic reviews and clinical trials are conducted and reported.
  • Qualitative reviews synthesize qualitative evidence to address questions on aspects of interventions other than effectiveness.

The CHBG has been mostly producing systematic reviews of interventions which include comparisons between pairs of interventions (an experimental intervention and a comparator intervention) for a specific condition and in a specific population or setting. The CHBG has also done some work on systematic reviews of interventions with network meta-analysis. In these reviews, numerous interventions available for a given condition are compared in order to present their comparative effectiveness and potential to harm.

The CHBG has also been producing diagnostic test accuracy reviews. 

All types of CHBG systematic reviews are preceded by a publication of a peer reviewed protocol and are published in the Cochrane Database of Systematic Reviews (CDSR) in The Cochrane Library.

The CHBG assembles a Hepato-Biliary Controlled Trials Register. The CHBG Controlled Trials Register is published in The Cochrane Central Register of Controlled Trials (CENTRAL).

The CHBG activities follow the policy and principles of Cochrane.

Clinicians, researchers, healthcare consumers, and people with many other different professions contribute to the work of The CHBG from different parts of the world.